Vayne & Senna vs Seraphine & Nautilus
Bot Lane Matchup
You
VS
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Who Wins
- You lose pre-6 due to Nautilus's engage threat and your short range against Seraphine poke.
- Post-6 you win with R stealth allowing you to outplay their engage and deal with Seraphine's immobility.
Synergy & Trading
- Trade with Q-auto-E when Nautilus abilities are down, using minions to block Seraphine Q.
- Focus on short trades rather than extended fights where their sustain and CC advantage you.
Wave Control/Roaming
- Freeze waves near your tower to deny Seraphine farm and force risky positioning for CS.
- Only push when you have clear recall timings or jungle assistance.
Mistakes to Avoid
- Don't get caught by Nautilus Q without your Q available for repositioning.
- Avoid fighting in Seraphine's optimal range where she can hit both you and Senna with abilities.
Created on 12/16/2025
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