Vayne & Nautilus vs Ezreal & Nami
Bot Lane MatchupVayne vs Ezreal (with Nautilus & Nami) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
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Who Wins
- You lose pre-6 2v2s due to short range and weak early trading against Ezreal's Q poke and Nami's sustain.
- Post-6 you win all-ins if you can get on top of Ezreal with R stealth and Nautilus engage.
Synergy & Trading
- Trade only when Nautilus lands Q hook or when Ezreal wastes E, using Q to reposition and proc W silver bolts for short burst trades.
- Avoid extended trades without your support's CC since Nami can disengage with Q bubble.
Wave Control/Roaming
- Farm safely and let the wave push toward you early to set up Nautilus hooks near your tower.
- Only push when you have vision and can recall safely, as you're vulnerable to ganks without escape tools pre-6.
Mistakes to Avoid
- Don't try to match Ezreal's poke trades early game as you'll lose the sustain war against Nami's W.
- Avoid using Q aggressively without vision since you have no other escape tools if caught out of position.
Created on 02/24/2026
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