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Thresh & Caitlyn vs Tristana & Milio

Bot Lane Matchup

Thresh vs Tristana (with Caitlyn & Milio) BOT matchup tips: who wins, how to trade, wave control and common mistakes.

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Who Wins

Pre-6, you win the 2v2 with Caitlyn because your hook threat alone forces Milio to play back, and Caitlyn's range means Tristana cannot safely farm without eating poke.
Post-6, your R combined with Caitlyn's trap is a near-guaranteed kill if Milio's R is on cooldown, so baiting out his R before committing to the all-in is the correct approach.

Your best pattern is to use flay to interrupt Tristana's E jump or cancel her repositioning, then immediately hook Milio who is typically less mobile and more isolated.
Killing or forcing out Milio first removes Tristana's healing and shield, making her a free target for Caitlyn.

You should roam aggressively once Caitlyn has shoved the wave to tower, because Tristana has no reliable way to punish a roam without Milio's presence and Caitlyn can hold the lane safely.
Level 6 roams with your R are high-value because your box combined with a mid-lane engage is extremely difficult to escape.

Do not throw your hook recklessly at Tristana when she has Milio's E shield active — a blocked or missed hook gives Tristana a free window to stack E on Caitlyn and potentially burst her before your hook comes back up.

Created on 08/26/2026

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