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Nami & Vayne vs Ezreal & Thresh

Bot Lane Matchup

Nami vs Ezreal (with Vayne & Thresh) BOT matchup tips: who wins, how to trade, wave control and common mistakes.

You

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Who Wins

Pre-6, you and Vayne lose to an aggressive Thresh level 2 all-in if he lands Q — your Q bubble is the only tool to interrupt his chain, but it is slow and easy to dodge, so you cannot reliably prevent the combo.
Post-6, you win sustained fights because your W healing outpaces Ezreal's poke damage and your R can interrupt Thresh's engage or Ezreal's E escape, giving Vayne the time she needs to stack Silver Bolts.

Your best pattern is to keep W charges on Vayne proactively during poke phases, then use E on Vayne when she goes for an auto-attack trade to amplify her Silver Bolts damage and slow the enemy.
Save your Q for interrupting Thresh's post-hook follow-up rather than trying to initiate with it, as the slow projectile is too easy to dodge in open trades.

You should not roam early — Vayne is extremely vulnerable to Thresh dives without your healing, and leaving her alone against a Thresh-Ezreal lane is a near-guaranteed death.
After level 6, if the wave is pushed and Vayne has enough sustain items, a quick mid roam with R can be impactful, but only when the wave is crashing into the enemy tower.

Do not spam W on Vayne for minor poke — you have limited mana and Thresh-Ezreal will outlast you in a war of attrition if you run dry.
Reserve W for meaningful trades or when Vayne drops below 70% health, and use E more aggressively to enable her Silver Bolts stacking.

Created on 06/30/2026

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