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Karthus & Nami vs Yunara & Nautilus

Bot Lane Matchup

Karthus vs Yunara (with Nami & Nautilus) BOT matchup tips: who wins, how to trade, wave control and common mistakes.

You

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Who Wins

Pre-6, you have a meaningful advantage through consistent Q poke — Yunara is immobile and must walk up to farm, making her a free target every time she steps forward, and Nautilus cannot always be in position to peel.
Post-6, you lose the 2v2 because Yunara's R transforms her into a sustained damage machine that outlasts your burst, and Nami's healing cannot keep up with her on-hit output in a prolonged fight.

Zone Yunara off CS with Q poke whenever she steps up, and use Nami's E empowered auto to set up a full trade when Nautilus is out of position or his hook is on cooldown.
Avoid extended fights at all costs — your passive only triggers on death, and Yunara's R makes her deal enough damage to kill you before your passive becomes relevant.

Push the wave with Q to deny Yunara easy farming and force her to take poke — a shoved wave also reduces the window where Nautilus can hook you in the open river.
Do not freeze; a frozen wave near your tower gives Nautilus a safe hook angle and lets Yunara farm freely while you take poke.

Do not stand still while Nautilus has his hook available — your lack of mobility is your biggest weakness, and a single hook into Nami's bubble is a death sentence before you can cast enough Qs to matter.
Always position behind minions and track Nautilus's hook cooldown to avoid being the primary engage target.

Created on 08/09/2026

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