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Zilean & Caitlyn vs Miss Fortune & Nami

Bot Lane Matchup

Zilean vs Miss Fortune (with Caitlyn & Nami) BOT matchup tips: who wins, how to trade, wave control and common mistakes.

You

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Who Wins

Pre-6, you win because your Q+W double-bomb combo on Miss Fortune forces her to either take massive poke or retreat, and she has no dash to dodge it reliably — Nami's healing cannot keep pace with sustained bomb harassment.
Post-6, your R completely neutralizes Miss Fortune's R as a kill threat, and your own kill pressure with R+slow is stronger than anything Nami can offer defensively.

Use Q to land a bomb on Miss Fortune, immediately follow with W to detonate it, then use your second Q on the slowed target to stack another bomb — this two-bomb rotation deals enormous burst and forces Nami to burn W.
Save E for your Caitlyn when she commits to a headshot trade, not as an opener, so she can safely walk up and proc it without being kited back.

You should not roam aggressively because your value in this lane is too high — Caitlyn needs your slows and R to safely convert leads, and leaving her alone against Miss Fortune's poke and Nami's engage is a significant risk.
If you do roam, only do so after pushing the wave under their tower post-6 when Caitlyn has enough items to sustain short trades alone.

Do not waste both Q charges on minions trying to poke, as you need the double-bomb rotation available for when Miss Fortune steps up — a single bomb without the detonation does far less pressure.
Avoid using R reactively after Miss Fortune has already channeled her R for more than one second, as the damage will have largely resolved before your ally revives.

Created on 08/21/2026

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