Vayne & Lux vs Kog'Maw & Seraphine

Vayne
You
Lux
VS
Kog'Maw
Seraphine

Tap any portrait to switch perspective

Who Wins

  • Pre-6: You lose poke trades but can win all-ins if you dodge Lux Q and get on top of Kog'Maw with Q positioning.
  • Post-6: You have kill pressure on Kog'Maw but must respect Seraphine's R engage and Lux's burst combo.
Confused by a term? Check the Glossary

Synergy & Trading

  • Use Q to dodge Seraphine Q poke, then look for short trades with W procs when Lux follows up with E.
  • Focus Kog'Maw in extended fights since he's immobile and easier to stack W on.

Wave Control/Roaming

  • Let them push early levels, then look to freeze and run them down when they overextend.
  • Use bushes to break vision and create engage angles that bypass their poke.

Mistakes to Avoid

  • Don't get poked down before committing to all-ins, as you need high HP to survive their burst combo.
  • Avoid fighting in minion waves where Seraphine can hit both you and Lux with her abilities.
Created on 04/02/2026
🛠️ Something wrong?