Thresh & Ezreal vs Caitlyn & Seraphine
Bot Lane MatchupThresh vs Caitlyn (with Ezreal & Seraphine) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
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VS
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Who Wins
- You lose pre-6 as Seraphine's poke and sustain outweigh your hook threat, especially with Caitlyn's range keeping her safe.
- Post-6 your R gives better all-in potential, but their range advantage and Seraphine R make teamfights difficult.
Synergy & Trading
- Look for Q angles when Ezreal is farming, then immediately follow with E-auto-ignite while he follows up with damage.
- Use W to help Ezreal engage or escape, and save R for when enemies are already committed to fights.
Wave Control/Roaming
- Roam when the wave is pushing toward your tower and Ezreal can farm safely, targeting mid lane around levels 3-5.
- Time roams around jungle objectives or when enemy mid is overextended, but communicate clearly with Ezreal about your absence.
Mistakes to Avoid
- Don't throw random hooks into Seraphine when her E is available, as missing gives them a free trading window.
- Avoid roaming when Ezreal is in a bad spot or when large waves are crashing, as he cannot survive 1v2 pressure.
Created on 06/06/2026
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