Caitlyn & Seraphine vs Ezreal & Thresh
Bot Lane MatchupCaitlyn vs Ezreal (with Seraphine & Thresh) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
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Who Wins
- You win pre-6 trades due to superior range and Seraphine's poke, but Ezreal's Q poke and Thresh's all-in potential keep it close.
- Post-6 you maintain advantage through range control and R execution, though Thresh R can turn fights if you're caught.
Synergy & Trading
- Auto-attack Ezreal when he goes for CS, then immediately step back while Seraphine follows with Q for extended trades.
- Use W-E combo when Thresh misses Q to force longer trades where your range advantage dominates.
Wave Control/Roaming
- Push early waves to establish range control and deny Ezreal easy Q angles through minions.
- Maintain slow pushes to keep minion advantage while using your range to zone, but be ready to thin waves if Thresh roams.
Mistakes to Avoid
- Don't use E aggressively for damage when Thresh Q is available, as getting hooked without escape guarantees death.
- Avoid standing in minion waves where Ezreal can Q you while farming, forcing you to choose between CS and taking poke.
Created on 06/06/2026
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