Seraphine & Ezreal vs Caitlyn & Nautilus
Bot Lane Matchup
You
VS
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Who Wins
- Caitlyn-Nautilus wins pre-6 through superior range control and hook threat limiting your positioning.
- Post-6 the matchup becomes more even as your R provides strong counter-engage, but they still hold lane priority through better wave control.
Synergy & Trading
- Use E to slow enemies when they step up for trades, allowing Ezreal to land guaranteed Q hits.
- Follow up with Q-W combo for damage and healing, but only commit to extended trades when Nautilus hook is down.
Wave Control/Roaming
- Roam when the wave is pushing toward enemies and Nautilus has backed or is low on mana.
- Optimal timings are after successful recalls when you have item advantages, focusing on mid lane ganks with your R engage potential.
Mistakes to Avoid
- Don't use E defensively unless Nautilus has already committed his Q, as wasting your only disengage tool leaves you vulnerable.
- Avoid face-checking brushes without vision, as Nautilus hook from fog of war is often unavoidable.
Created on 12/10/2025
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