Ezreal & Seraphine vs Caitlyn & Nautilus

Ezreal
You
Seraphine
VS

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Who Wins

  • Caitlyn wins pre-6 due to superior range and Nautilus's hook threat forcing you into defensive positioning.
  • Post-6 you gain kill pressure with your R execute potential, but Caitlyn still controls the lane through superior range and wave management.

Synergy & Trading

  • Use Q poke when Nautilus is out of hook range, then immediately back off to avoid retaliation.
  • Coordinate with Seraphine's E slow to land guaranteed Q hits and follow up with W-auto for burst trades.

Wave Control/Roaming

  • Focus on freezing near your tower to deny Caitlyn's range advantage and force overextensions.
  • Only push when you have clear vision and can safely recall, as Caitlyn excels at punishing bad recalls with tower damage.

Mistakes to Avoid

  • Never E forward aggressively without flash up, as Nautilus hook into Caitlyn follow-up is lethal.
  • Don't waste mana on Q poke when the wave is pushing toward them, as you'll need it for last-hitting under tower.
Created on 12/10/2025
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