Nautilus & Caitlyn vs Ezreal & Seraphine

Nautilus
You
Caitlyn
VS

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Who Wins

  • You win pre-6 through hook threat and superior all-in potential with Caitlyn's follow-up damage.
  • Post-6 you maintain advantage but must be more cautious of Seraphine's R counter-engage disrupting your combos.

Synergy & Trading

  • Look for hook opportunities when enemies step up for CS or when Seraphine uses abilities on minions.
  • Follow successful hooks with W-E combo while Caitlyn places W trap behind the target for guaranteed headshot execution.

Wave Control/Roaming

  • Roam when your ADC has wave control and enemies are low on mana or abilities.
  • Best timings are after forcing enemies to recall or when you have level advantages, focusing on mid lane or jungle skirmishes.

Mistakes to Avoid

  • Don't hook through minions unless you're certain of the angle, as missing leaves your ADC vulnerable for 12+ seconds.
  • Avoid using W proactively in trades unless you've already landed hook, as you need the shield for enemy retaliation.
Created on 12/10/2025
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