Senna & Caitlyn vs Ezreal & Milio
Bot Lane Matchup
You
VS
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Who Wins
- You lose level 2 all-ins due to Milio's W shield and sustain negating your poke advantage, but win level 6 trades with R execute potential and Caitlyn's R follow-up.
- Ezreal's E makes him slippery but your W root can still catch him if he mispositions.
Synergy & Trading
- Your optimal trading is Q poke into Caitlyn headshot follow-up, then back off before Milio can W shield the return damage.
- Focus on stacking souls through Q minion piercing while Caitlyn zones with traps, creating safe poke windows.
Wave Control/Roaming
- Push early levels to stack souls and deny Ezreal farm, but transition to freezing once Ezreal gets Sheen since he can waveclear safely.
- Your range advantage with Caitlyn allows you to maintain minion control while threatening dives.
Mistakes to Avoid
- Don't overextend for soul collection when Milio has W available, as his shield plus Ezreal's E creates easy escape routes.
- Avoid using W aggressively without Caitlyn trap setup since Ezreal can E away and Milio can cleanse the root.
Created on 11/19/2025
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