Caitlyn & Senna vs Ezreal & Milio
Bot Lane Matchup
You
VS
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Who Wins
- You lose level 2 due to Milio's sustain and shield negating your headshot poke, but win level 6 with R execution combined with Senna's R damage.
- Your range advantage becomes more pronounced as the game progresses and Ezreal struggles to match your zone control.
Synergy & Trading
- Your best pattern is headshot auto after Senna Q, then E backwards if they engage while placing W traps to zone retreat paths.
- Use Q through minions when Ezreal is farming to force Milio W usage before major trades.
Wave Control/Roaming
- Maintain slow pushes to build minion advantages for trap placement, but avoid hard shoving since Ezreal can Q farm safely under tower.
- Freeze when ahead to deny Ezreal farm while using your range to threaten dives with jungle assistance.
Mistakes to Avoid
- Don't waste E aggressively since Ezreal's E cooldown is shorter and Milio can cleanse your W slow.
- Avoid using R when Milio has W available unless the target is already very low, as the shield can negate your execution potential.
Created on 11/19/2025
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