Ezreal & Milio vs Caitlyn & Senna
Bot Lane Matchup
You
VS
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Who Wins
- You win level 2 all-ins with Milio's W shield and sustain advantage, but lose level 6 due to double ultimate execution potential from both enemies.
- Your mobility advantage decreases as Senna gains range and Caitlyn's trap control improves.
Synergy & Trading
- Your best trading is Q poke when enemies are farming, then E away before Senna can W root you while Milio provides W shield.
- Focus on short Q trades rather than extended fights since their combined range advantage grows over time.
Wave Control/Roaming
- Farm safely with Q and avoid pushing waves since their range advantage makes you vulnerable to ganks and poke.
- Let them push into you where Milio can provide better protection and you have shorter distances to escape.
Mistakes to Avoid
- Don't E forward aggressively since Senna W and Caitlyn W can lock you down despite your mobility.
- Avoid extended trades even with Milio support since their combined damage output and range advantage will win longer engagements.
Created on 11/19/2025
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