Pyke & Twitch vs Caitlyn & Nautilus

Pyke
You
Twitch
VS

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Who Wins

  • You struggle pre-6 against Nautilus's superior engage and tankiness, but post-6 your R execute potential and mobility make you the stronger support in skirmishes.
  • Your E can interrupt Nautilus's Q but requires precise timing.

Synergy & Trading

  • Use E to engage when Twitch is in position to follow up, or use Q to pull enemies into Twitch's range for trades.
  • Your W allows you to reposition for better angles and escape Caitlyn's long-range poke.

Wave Control/Roaming

  • Roam frequently after level 3, especially to mid lane where your E+Q combo can secure kills, but ensure Twitch can farm safely under tower first.
  • Look for roam timings when Caitlyn recalls or when waves are pushing toward your tower.

Mistakes to Avoid

  • Don't engage with E unless you're certain of the follow-up damage, as missing it leaves you vulnerable to Nautilus's counter-engage.
  • Avoid staying in Caitlyn's auto range without W movement speed, as her headshot trades will chunk you significantly.
Created on 12/08/2025
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