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Who Wins
- Pre-6, your Q poke and W polymorph on Nautilus when he attempts to hook are strong defensive tools, and combined with Caitlyn's range you win the sustained poke phase clearly.
- Post-6, you remain favored but must respect Nautilus's R — if his R lands on Caitlyn, you must immediately use your R on her to knock Nautilus away and save her, making cooldown tracking critical.
Synergy & Trading
- Your best pattern is to Q poke Miss Fortune when she steps up, use W to polymorph Nautilus the moment he lands his Q hook to interrupt his chain, and save E shield for Caitlyn when she takes headshot or Q poke damage.
- Do not use W aggressively on Miss Fortune — save it as a defensive tool against Nautilus's engage.
Wave Control/Roaming
- You should generally not roam in this matchup — Caitlyn is vulnerable to Nautilus's all-in without your peel, and leaving her alone against a hook champion is high risk.
- If you do roam, only do so after a shoved wave with Caitlyn safely under tower and Nautilus's Q on cooldown, targeting mid for a quick R setup.
Mistakes to Avoid
- Do not use your W offensively on Miss Fortune during laning phase when Nautilus is alive and untracked — burning W for poke damage leaves Caitlyn exposed to a hook chain with no interrupt available.
- Prioritize W as a defensive tool against Nautilus's engage over using it as a poke ability.
Created on 08/30/2026
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