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Karma & Ezreal vs Seraphine & Swain

Bot Lane Matchup

Karma vs Seraphine (with Ezreal & Swain) BOT matchup tips: who wins, how to trade, wave control and common mistakes.

You

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Who Wins

Pre-6, you and Ezreal win: your empowered E on Ezreal negates Swain's engage pattern, your Q poke is reliable, and Seraphine's CC is too slow to punish a mobile Ezreal.
Post-6, Seraphine's R is a genuine threat to both of you simultaneously, so you must respect her positioning and avoid clustering with Ezreal.

Your best pattern is to use empowered E on Ezreal proactively before Swain attempts his W pull, then follow with a Q aimed at Swain to punish his forward position.
When Seraphine stacks her passive for an empowered Q, use your W on Ezreal immediately to give him a movement speed boost to dodge it rather than tanking the heal-denying poke.

You should not roam in this matchup — Swain post-6 is a roam threat himself, and leaving Ezreal alone against Seraphine's wave clear and Swain's engage is a death sentence for your ADC.
Stay in lane, maintain priority, and only consider a roam if both enemies have backed and the wave is frozen safely near your tower.

Do not use your R on Q to poke Seraphine when Swain is in a position to engage — burning your mantra on damage rather than saving it for a defensive empowered E on Ezreal leaves him exposed to a Swain all-in with no escape tool.
Prioritize defensive mantra usage in this matchup over aggressive poke patterns.

Created on 08/14/2026

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