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Ezreal & Karma vs Seraphine & Swain

Ezreal
You
Karma
VS

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Who Wins

  • Pre-6, you and Karma win the lane: your Q poke is safe, Karma's E gives you a shield and movement speed to disengage any Swain engage attempt, and Seraphine's CC is slow enough that you can blink out with E.
  • Post-6, Seraphine's R is a lane-wide threat and Swain's R makes sustained fights dangerous, so you must avoid letting them dictate a prolonged all-in.

Synergy & Trading

  • Your best pattern is to Q poke Seraphine repeatedly to stack her healing costs and force Swain to play passively, then use your E to reposition laterally rather than backward when Seraphine throws her E — sidestepping the root entirely removes their all-in setup.
  • When Karma empowers your E with her R, use that window to burst Seraphine before Swain can engage.

Wave Control/Roaming

  • Keep the wave in a slow push toward their side or freeze it near your tower — Swain has poor wave clear and is forced to walk up to CS, giving you free Q poke opportunities.
  • Avoid hard-pushing into their tower, as a shoved wave gives Swain and Seraphine roam priority and removes your safe farming position.

Mistakes to Avoid

  • Do not use your E aggressively to close distance on Seraphine — it wastes your only escape tool and puts you inside Swain's W pull range.
  • Your win condition is sustained poke from range, not all-ins, so treat your E as a defensive repositioning tool at all times in this matchup.
Created on 08/14/2026
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