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Ezreal & Nautilus vs Seraphine & Heimerdinger

Ezreal
You
Nautilus
VS

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Who Wins

  • Pre-6, you and Nautilus win this lane — Nautilus level 2 hook-root combo forces Seraphine and Heimerdinger to play extremely passive, and your Q poke punishes any overextension while they struggle to set up turrets.
  • Post-6, the lane becomes more dangerous because Seraphine R can chain into Heimerdinger R-grenade for a full wombo, so you need to respect their all-in range.

Synergy & Trading

  • Your best pattern is to Q poke Seraphine or Heimerdinger whenever they step up to place turrets or stack passive, then let Nautilus engage only when one of them is low enough that your W blink-in follow-up secures the kill without overextending.

Wave Control/Roaming

  • You want to avoid letting the wave freeze under their turrets where Heimerdinger's turrets have permanent uptime — instead, contest the wave in the middle of the lane where Nautilus can threaten hooks in open space and your Q range is maximized.

Mistakes to Avoid

  • Do not use your E blink aggressively to dodge Heimerdinger's E stun and then find yourself inside turret range with no escape — your E is your only reliable out against Seraphine R + Heimerdinger R follow-up, and burning it offensively leaves you dead.
Created on 06/28/2026
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