Zyra & Caitlyn vs Miss Fortune & Nautilus

Zyra
You
Caitlyn
VS

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Who Wins

  • You win level 2 trades with E-Q-W combo and plant damage being superior to Nautilus Q engage potential.
  • You lose level 6 fights if Nautilus lands Q-R on either carry, as your R knockup cannot interrupt Miss Fortune's R channel during hard crowd control.

Synergy & Trading

  • Place W seeds aggressively when Nautilus misses Q, then E-Q combo to proc plants for maximum poke damage.
  • Use plants to zone Miss Fortune from Q bounce angles while maintaining distance from Nautilus hook range.

Wave Control/Roaming

  • Avoid roaming as your plants provide crucial zone control against Nautilus engages and Miss Fortune positioning.
  • Focus on deep warding river and maintaining plant coverage in lane bushes to prevent flanks.

Mistakes to Avoid

  • Never use E defensively to disengage if Miss Fortune has R available, as you need it to interrupt her channel.
  • Avoid clumping with Caitlyn during team fights, as Miss Fortune R hits multiple targets for increased damage.
Created on 11/27/2025
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