Nautilus & Miss Fortune vs Caitlyn & Zyra
Bot Lane Matchup
You
VS
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Who Wins
- You lose level 2 trades due to Zyra's superior poke and disengage with E-W-Q combo against your single Q engage.
- You win level 6 fights with successful Q-R combo as your lockdown duration exceeds Zyra's peel potential for Miss Fortune's R channel.
Synergy & Trading
- Look for Q angles through minion waves when Caitlyn steps forward for CS or trap placement.
- Follow successful hooks with W-E combo while Miss Fortune channels R, using your body to block Zyra's skill shots.
Wave Control/Roaming
- Roam mid or jungle after pushing waves level 4-5 when Miss Fortune can clear safely with Q bounces.
- Time roams when Zyra uses plants for wave clear, as she becomes vulnerable without her zone control tools.
Mistakes to Avoid
- Never Q engage without Miss Fortune in position to follow up with R, as you'll be isolated against two champions with strong disengage.
- Avoid walking directly at them through minion waves where Zyra can land free E-Q combos.
Created on 11/27/2025
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