Who Wins
- You lose pre-6 due to Vayne's range advantage and Lulu's poke/disengage, but post-6 you can win all-ins if you land E-Q3 combo on either target.
- Your level 3 spike with E-Q-W gives you brief trading windows but isn't enough to overcome their range control.
Synergy & Trading
- Look for E forward when Lulu uses Q or W on minions, then Q3-W-auto-Q reset for quick trades before retreating.
- Coordinate with Yasuo's tornado to guarantee your Q3 knockup, creating extended CC chains that force summoners or kills.
Wave Control/Roaming
- Push early levels to hit your powerspikes first, then look to freeze near your tower post-6 where you can run them down with E.
- Avoid slow pushing mid-game as Vayne excels at kiting in long lanes.
Mistakes to Avoid
- Don't E forward without Yasuo's tornado ready or when Lulu has W available to polymorph you mid-dash.
- Going in when the wave is pushing toward them gives Vayne too much space to kite backward.
Created on 02/25/2026
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