Varus & Thresh vs Miss Fortune & Zyra

Varus
You
Thresh
VS
Miss Fortune
Zyra

Tap any portrait to switch perspective

Who Wins

  • Pre-6 you lose most trades due to Miss Fortune's Q bounce damage and Zyra's plant setup, but can win if Thresh lands Q on either enemy.
  • Post-6 you win all-ins if you land R on Miss Fortune before she can R, as your chain CC with Thresh becomes lethal.
Confused by a term? Check the Glossary

Synergy & Trading

  • Poke with Q when enemies are lined up or behind minions, then follow up with W-auto-E when Thresh lands Q for maximum burst.
  • Always save your R to counter Miss Fortune's R channel or to set up Thresh's follow-up CC.

Wave Control/Roaming

  • Push early levels to get level 2 first and avoid extended trades in minion waves where Miss Fortune excels.
  • Keep the wave in the center or slightly pushed to give Thresh angles for Q without being punished by Zyra's zone control.

Mistakes to Avoid

  • Never use R defensively unless it's to interrupt Miss Fortune's R - you need it to win fights offensively.
  • Don't try to out-sustain this lane as you have no healing and will get poked down by superior range and damage.
Created on 05/18/2026
🛠️ Something wrong?