Varus & Nautilus vs Ezreal & Seraphine
Bot Lane MatchupVarus vs Ezreal (with Nautilus & Seraphine) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
You
VS
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Who Wins
- You lose pre-6 due to Ezreal's superior mobility and Seraphine's sustain negating your poke advantage.
- Post-6 you win if Nautilus lands R on either enemy, as your R follow-up creates guaranteed kills.
Synergy & Trading
- Look for Q poke when enemies are CSing, then follow Nautilus hook attempts with immediate W-E-Q combo for maximum burst.
- Your trading revolves around Nautilus creating picks rather than sustained trades.
Wave Control/Roaming
- Push early waves to establish vision control and enable Nautilus roams, but avoid overextending without flash.
- Focus on freezing when ahead to deny Ezreal farm and create gank opportunities.
Mistakes to Avoid
- Don't waste R defensively unless it's a guaranteed kill setup - Ezreal's E makes him hard to catch, so save R for when Nautilus has already committed his engage tools.
Created on 06/14/2026
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