Nautilus & Varus vs Ezreal & Seraphine
Bot Lane MatchupNautilus vs Ezreal (with Varus & Seraphine) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
You
VS
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Who Wins
- You lose pre-6 as Seraphine outranges your engage and sustains through your damage while Ezreal kites your all-ins.
- Post-6 your R guarantees picks if you can get in range, making you the stronger 2v2.
Synergy & Trading
- Walk up aggressively to zone enemies from CS, forcing them to respect your Q threat, then look for hooks when they're animation-locked.
- Your trades are all-or-nothing - either land Q for full combo or disengage immediately.
Wave Control/Roaming
- Roam after pushing waves level 4-6 when your R becomes available, focusing on mid lane picks.
- Time roams when Ezreal backs or when you have minion advantage to prevent tower damage.
Mistakes to Avoid
- Don't hook through minions early game unless it's a guaranteed kill - missing Q leaves Varus exposed to Seraphine poke and Ezreal all-ins for 18+ seconds.
Created on 06/14/2026
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