Thresh & Kalista vs Kai'Sa & Nautilus

Thresh
You
Kalista
VS

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Who Wins

  • You win level 2 all-ins with Q-E combo enabling Kalista's E burst and mobility advantage over Kai'Sa's limited escape options.
  • At level 6, you maintain edge through R displacement and Kalista R saves, though Nautilus R becomes more reliable engage.

Synergy & Trading

  • Look for Q angles when Kai'Sa steps up for CS or when Nautilus misses his Q, then follow with E-auto-ignite while Kalista commits with E stacks.
  • Use W to reposition Kalista for better kiting angles or to save her from Nautilus all-in attempts.

Wave Control/Roaming

  • Roam mid or jungle at levels 3-5 when Kalista can safely 1v1 Kai'Sa and the wave state allows it.
  • Time roams after successful trades that force enemies low or after they recall, ensuring Kalista won't be dove by enemy jungler.

Mistakes to Avoid

  • Never waste Q on minions when enemies are in aggressive positions, as it's your primary tool for both engage and disengage.
  • Avoid using E defensively too early in trades, as you need it to interrupt Nautilus Q or to follow up your own Q for maximum damage.
Created on 11/27/2025
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