Nautilus & Kai'Sa vs Kalista & Thresh

Nautilus
You
Kai'Sa
VS

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Who Wins

  • You lose level 2 fights because Thresh Q-E combo with Kalista follow-up outdamages your Q-W-E combo with Kai'Sa's limited early damage.
  • At level 6, you gain slight advantage as your R guarantees lockdown while Thresh R can be cleansed or flashed.

Synergy & Trading

  • Look for Q angles when Kalista is animation-locked during CS or when Thresh is out of position to counter-engage.
  • Follow successful Q with W-E-auto combo while Kai'Sa adds W-Q damage, then disengage before Kalista can stack E effectively.

Wave Control/Roaming

  • Roam mid at level 3-4 when the wave is pushing toward Kalista and your ADC can safely farm under tower.
  • Time roams when Thresh recalls or when enemy bot lane is low and forced to back, ensuring you don't leave Kai'Sa in a 1v2.

Mistakes to Avoid

  • Never Q forward without vision of enemy jungler or when Kalista has flash up and multiple E stacks on your ADC.
  • Avoid using W for poke trades as you need it for all-in combos and the mana cost is too high for lane sustain.
Created on 11/27/2025
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