Seraphine & Twitch vs Lucian & Karma

Seraphine
You
Twitch
VS

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Who Wins

  • You lose pre-6 due to longer cooldowns and less burst compared to Karma's consistent poke, but post-6 your R gives strong engage potential if you can land it on both enemies.
  • Your main goal is surviving lane phase while providing sustain for Twitch.

Synergy & Trading

  • Use Q for safe poke and immediately W for the heal/shield when they trade back, focusing on sustaining Twitch rather than winning trades outright.
  • Your best trading windows come after Karma uses Q, when you can Q+W without taking significant return damage.

Wave Control/Roaming

  • Don't roam early as Twitch needs your sustain and protection to survive the lane - your presence is more valuable than roam attempts.
  • Consider roaming only after first back when you have mana items and Twitch can safely farm alone.

Mistakes to Avoid

  • Don't try to match Karma's poke frequency early game as your mana costs are higher and cooldowns longer.
  • Avoid using R defensively unless it's a guaranteed life-save, as it's your only real engage tool for mid-game teamfights.
Created on 01/03/2026
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