Who Wins
- You dominate pre-6 with superior mobility and burst through E+Q+W combos, but post-6 becomes more dangerous due to Seraphine's R engage potential.
- Your level 2 power spike with E+Q is particularly strong for early trades.
Synergy & Trading
- Use E aggressively to dash forward for Q+W+passive procs when Karma lands Q poke, then immediately dash back or use Karma's E shield for safety.
- Your burst combo works best when Karma's W root guarantees your full rotation hits.
Wave Control/Roaming
- Push hard early levels to establish lane priority and deny Twitch's scaling, but be ready to freeze if you get a significant health advantage.
- Control the wave to set up dives with your jungler since Twitch has no reliable escape pre-6.
Mistakes to Avoid
- Don't E forward without Karma's E shield or W root setup, as Seraphine's Q+W sustain can out-trade your burst if you take too much return damage.
- Avoid extended trades where Twitch's passive poison stacks become meaningful.
Created on 01/03/2026
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