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Seraphine & Ashe vs Ziggs & Camille

Bot Lane Matchup

Seraphine vs Ziggs (with Ashe & Camille) BOT matchup tips: who wins, how to trade, wave control and common mistakes.

You

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Who Wins

Pre-6, you and Ashe win clearly — your E root stops Camille's engage cold and your combined poke with Q and Ashe W makes it nearly impossible for Ziggs to farm safely.
Post-6, your R into Ashe R chain is a fight-winning combo, but you must respect Ziggs' R range as it can execute low-health targets from outside your vision.

Your best pattern is to use E to root Camille whenever she attempts to E-dash, then immediately follow with Q for the slow and Ashe W autos for the burst — this two-step lockdown removes Camille's entire kit.
In poke phases, use Q on cooldown to stack your passive and keep your shield available to absorb Ziggs' Q harassment.

You should generally not roam — your value is in enabling Ashe's kiting pattern and providing the E root that makes the lane unplayable for Camille.
If Ashe recalls and the wave is pushed, you can look for a quick mid roam with R, but only if Camille is recalled or dead so she cannot dive Ashe on your return.

Do not waste E on Ziggs when Camille is alive and threatening — your root is your primary anti-engage tool and using it on the wrong target gives Camille a free engage window.
Avoid over-committing to healing Ashe during extended trades when Ziggs is in range; his Q damage will outpace your heals if you stand still to channel.

Created on 07/06/2026

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