Senna & Nautilus vs Samira & Thresh
Bot Lane MatchupSenna vs Samira (with Nautilus & Thresh) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
You
VS
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Who Wins
- You win pre-6 2v2s through superior range, poke damage, and Nautilus's engage/peel combination.
- Post-6 you maintain advantage but must respect Thresh R into Samira R combo potential in close quarters.
Synergy & Trading
- Use Q to poke and heal simultaneously while collecting souls, then follow up with auto attacks when Thresh misses Q.
- Position behind Nautilus when he engages to maximize your damage output while staying safe.
Wave Control/Roaming
- Maintain slow push to accumulate souls while staying in safe positions, using your range advantage to zone enemies from farm.
- Look to crash waves before backing to prevent Samira from free farming under tower.
Mistakes to Avoid
- Don't greed for souls in dangerous positions when Thresh Q is available - your immobility makes you vulnerable to hook into Samira combo.
- Avoid face-checking bushes without Nautilus nearby as Thresh can easily set up picks.
Created on 06/08/2026
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