Nautilus & Hwei vs Zeri & Milio

Nautilus
You
Hwei
VS

Tap any portrait to switch perspective

Who Wins

  • You lose level 2 all-ins due to Milio's cleanse and heal negating your hook engage, but you win level 6 fights if you can land hook on Zeri since your ultimate guarantees follow-up damage from Hwei.
  • Zeri's mobility makes her difficult to catch, but once locked down she's extremely vulnerable.

Synergy & Trading

  • Look for hook opportunities when Zeri uses her dash aggressively or when Milio is out of position to cleanse immediately.
  • Follow up your hook with auto-attack and E, then let Hwei land his combo while you body-block Zeri's escape routes.

Wave Control/Roaming

  • You should roam frequently after level 6 since this lane matchup favors scaling and Hwei can waveclear safely.
  • Optimal roam timings are when the wave is pushing toward your tower and mid lane has gankable positioning around 8-12 minutes.

Mistakes to Avoid

  • Don't waste your hook on Milio unless it's a guaranteed kill setup, as his cleanse will negate most of your engage potential.
  • Avoid hooking when Zeri has her ultimate up and multiple walls nearby, as she can easily escape your follow-up.
Created on 11/16/2025
🛠️ Something wrong?