Lulu & Vayne vs Smolder & Milio
Bot Lane Matchup
You
VS
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Who Wins
- You win level 2 fights with W polymorph disrupting Smolder's damage while Vayne follows up with Q-AA-E combos.
- Level 6 remains strongly in your favor as your R provides instant survivability that counters Smolder's R execute while Vayne's stealth makes Milio's abilities difficult to land.
Synergy & Trading
- Use W polymorph when Smolder tries to trade back after Vayne's Q-AA, then E Vayne for the shield and movement speed to extend the trade.
- Your Q should be used to slow Smolder's retreat, allowing Vayne to get additional auto attacks with W passive stacks.
Wave Control/Roaming
- Roam opportunities are limited in this matchup since Vayne needs your protection to maintain lane dominance.
- Only roam when Vayne has a significant health/item advantage and can safely 1v2, typically after securing kills or forcing enemy recalls.
Mistakes to Avoid
- Never use W polymorph defensively on Vayne unless she's guaranteed to die, as it's your primary tool for winning trades offensively.
- Avoid warding alone without Vayne nearby since Milio's Q-R combo can easily kill you if caught out of position.
Created on 11/27/2025
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