Lulu & Vayne vs Caitlyn & Lux

Lulu
You
Vayne
VS

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Who Wins

  • You lose pre-6 due to Lux's superior range and poke damage, with your W being your only reliable trading tool.
  • Post-6 the matchup improves significantly as your R can counter Lux burst while enabling Vayne's assassination potential on either target.

Synergy & Trading

  • Use W on Caitlyn when she steps up to auto Vayne, then shield Vayne to help her trade back effectively.
  • Look for E-Q poke combos when enemies are grouped or when Caitlyn uses E aggressively, as this creates windows for favorable trades.

Wave Control/Roaming

  • Avoid roaming early as Vayne needs constant protection and peel against this lane's poke pressure.
  • Only roam post-6 when Vayne has R available and can potentially 1v2, or when enemies recall and you can make plays elsewhere safely.

Mistakes to Avoid

  • Don't use W randomly for poke as the cooldown is long and Vayne needs it for protection against all-ins.
  • Never position where Lux can Q both you and Vayne simultaneously, as this removes all your peel potential and guarantees a lost fight.
Created on 12/04/2025
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