Lulu & Jinx vs Vayne & Karma

Lulu
You
Jinx
VS
Vayne
Karma

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Who Wins

  • You win level 2 fights decisively with polymorph and shield negating their damage output.
  • You start losing at level 6 when Karma gets empowered abilities and Vayne gets condemn for picks.
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Synergy & Trading

  • Polymorph Vayne when she tumbles forward for trades, then shield Jinx and let her follow up with rockets.
  • Use your E-Q combo to poke when Karma wastes her shield cooldown.

Wave Control/Roaming

  • You shouldn't roam much in this matchup since Jinx needs protection from Vayne's all-in potential.
  • Only roam when Vayne is very low or when you have a massive wave pushing into their tower.

Mistakes to Avoid

  • Don't waste polymorph on Karma when Vayne is the real threat in fights.
  • Avoid using your ultimate too early in fights, save it for when someone is actually in lethal range.
Created on 11/14/2025
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