Karma & Vayne vs Jinx & Lulu

Karma
You
Vayne
VS
Jinx
Lulu

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Who Wins

  • You lose level 2 all-ins due to Lulu's polymorph and shield negating your burst combo.
  • You win level 6 fights if you can land RQ on both enemies and follow up with Vayne's condemn for picks.
Confused by a term? Check the Glossary

Synergy & Trading

  • Poke with Q when Lulu is out of position or has used polymorph, then immediately shield Vayne if they retaliate.
  • Focus on landing empowered Q's when Jinx steps up to last hit minions.

Wave Control/Roaming

  • You should roam mid after shoving waves when Vayne has items to 1v2 safely, typically after her first back with BF sword.
  • Look for roam timings when enemy bot recalls or when mid lane is gankable around levels 4-6.

Mistakes to Avoid

  • Don't waste your empowered abilities on minions when enemies are in range for trades.
  • Avoid using shield reactively instead of proactively, as Lulu's burst combo happens too quickly to react to.
Created on 11/14/2025
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