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Locke & Anivia vs Senna & Lissandra
Bot Lane MatchupLocke vs Senna (with Anivia & Lissandra) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
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Who Wins
- Pre-6, Senna + Lissandra have the edge — Lissandra's Q poke and root deny your Q stacking setup, and Senna's range means you cannot safely walk up to apply nail stacks without eating significant damage; post-6, your R's 99% slow and execution threshold give you a kill window if you can stack Q on Senna first, but Lissandra's R hard-counters your E dash by displacing you mid-combo.
Synergy & Trading
- Stack Q on Senna from max range to build nail marks, then use E to dash in and consume stacks with your empowered attack before activating W to sustain through Lissandra's follow-up — the key is committing only when Lissandra's Q and R are on cooldown, as her CC will interrupt your E dash and waste your combo.
Wave Control/Roaming
- Play for a slow push into a freeze near your tower to force Senna to overextend for souls, as her passive requires her to walk up to collect them — this creates isolated moments where you can E onto her without Lissandra being in optimal position to peel.
Mistakes to Avoid
- Do not activate W reactively to Lissandra's R, because W does not cleanse CC and you will take true damage while still being frozen — W should be used proactively during your all-in to sustain through their combined burst, not as a panic button after you are already locked down.
Created on 08/27/2026
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