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Lissandra & Senna vs Locke & Anivia
Bot Lane MatchupLissandra vs Locke (with Senna & Anivia) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
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Who Wins
- Pre-6, you and Senna win the 2v2 — your Q poke and root deny Locke's Q stacking pattern and punish Anivia's immobility, and Senna's range means Anivia cannot safely walk up to trade; post-6, Anivia's R channel threatens to zone you off Senna and Locke's R execution mark creates a kill threat you cannot ignore, so your advantage narrows significantly.
Synergy & Trading
- Your best trading pattern is to Q poke Anivia to chunk her before her egg activates, then root Locke with Q if he tries to E in — if Locke commits to a full all-in, use your R on yourself to become untargetable and stall his W true damage window, then re-engage after his W expires.
Wave Control/Roaming
- You should roam when Anivia uses R to push the wave, as that is her longest cooldown and Locke cannot reliably 1v2 without your CC setup — roam mid at level 6 when your R is online, as your R + mid laner CC creates instant kill pressure that Anivia's wave clear cannot match in time to prevent.
Mistakes to Avoid
- Do not use your R offensively on Locke during his W activation, because he can recast W early to end it and heal back a significant portion of the damage — save your R as a defensive tool to make yourself untargetable when Locke's E + W combo is mid-execution, denying him the kill and wasting his cooldowns.
Created on 08/27/2026
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