Leona & Caitlyn vs Ezreal & Karma

Leona
You
Caitlyn
VS
Ezreal
Karma

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Who Wins

  • You win level 2 all-ins decisively with E-Q combo, and maintain kill pressure at level 6 through R engage setup.
  • Your tankiness and CC chain gives Caitlyn easy follow-up damage in extended trades.
Confused by a term? Check the Glossary

Synergy & Trading

  • Engage with E when Ezreal uses Q and is animation-locked, then immediately Q-W for maximum lockdown duration.
  • Coordinate with Caitlyn's trap placement to extend CC chain and guarantee her damage combo.

Wave Control/Roaming

  • Roam mid after successful trades or when Caitlyn has wave control and doesn't need protection.
  • Best timing is level 3-5 when your base damages are strong and enemies lack escape tools.

Mistakes to Avoid

  • Don't engage when Karma has R available for defensive usage, wait for her to use it offensively first.
  • Never use E through multiple minions where Ezreal can easily sidestep and avoid your engage.
Created on 11/22/2025
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