Zyra & Miss Fortune vs Aphelios & Karma

Zyra
You
Miss Fortune
VS

Tap any portrait to switch perspective

Who Wins

  • You win pre-6 through plant harassment and E setup, especially at level 2 with E+W combo.
  • Post-6 your R combined with Miss Fortune R creates lethal zone control, but Karma's R+E can mitigate significant damage.

Synergy & Trading

  • Use E to root targets for Miss Fortune's Q bounce or W+auto follow-up, then place plants to extend the trade duration.
  • Focus on poking Aphelios when he's farming with short-range weapons like Severum or Gravitum.

Wave Control/Roaming

  • Roam after pushing waves level 4-6 when Miss Fortune can hold lane safely, targeting mid lane ganks with E setup.
  • Time roams when Aphelios has Severum/Gravitum weapons since he can't clear waves quickly to follow.

Mistakes to Avoid

  • Don't waste E when Karma has W available to dash away, and avoid placing plants where Aphelios can clear them with Infernum Q splash.
  • Never engage without knowing Aphelios's current weapon combination since Gravitum R can turn fights instantly.
Created on 03/18/2026
🛠️ Something wrong?