Vladimir vs Vayne

Vladimir
You
VS
Vayne

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Who Wins

  • You lose early trades pre-6 due to Vayne's range advantage and consistent auto-attack damage, but you scale better into mid-game teamfights.
  • Post-6, you can win all-ins with R + full combo if you land E, as Vayne lacks burst mitigation and your sustain negates her poke.
Confused by a term? Check the Glossary

How to Trade

  • Use Q on minions for sustain and only trade when your empowered Q is ready, combining it with E for a quick burst before backing off.
  • Avoid extended trades where Vayne can proc multiple W stacks, and save W for dodging her E or escaping when low.

Wave Control

  • Push waves with E and Q to force Vayne under tower where she struggles to last-hit and harass simultaneously.
  • Maintain wave control to set up ganks, as Vayne has no reliable escape pre-6 besides flash and condemn positioning.

Mistakes to Avoid

  • Don't chase Vayne through minion waves where she can condemn you into walls for a stun.
  • Avoid fighting in open areas post-6 where her R gives her invisibility and kiting potential that negates your engage tools.
Created on 05/31/2026
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