Who Wins
- Caitlyn-Morgana wins pre-6 due to superior range, poke, and zone control with Q-W combo that outranges your Q heal sustain.
- Post-6 they maintain advantage as your R can't counter their burst potential and Black Shield negates your E silence.
Synergy & Trading
- Stay max range to land Q on enemies for self-heal, then immediately W Vayne after she takes poke damage.
- Focus on sustaining through their poke rather than engaging, as your kit excels at negating gradual damage over time.
Wave Control/Roaming
- You should never roam in this matchup as Vayne desperately needs your sustain to survive the poke lane.
- Your presence is essential to keep Vayne healthy enough to farm and scale.
Mistakes to Avoid
- Don't waste E aggressively when Morgana has Black Shield available, as she'll negate the silence and leave you vulnerable.
- Avoid face-checking bushes without vision as Morgana Q into Caitlyn combo can instantly delete you.
Created on 12/23/2025
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