Who Wins
- You win pre-6 through superior sustain and poke with Q power chord, but lose post-6 when Vel'Koz R can zone you completely and Vayne becomes too mobile to pin down.
- Your team lacks the burst to punish Vayne's short range effectively.
Synergy & Trading
- Use Q to poke both enemies when they're grouped, then immediately W to sustain any return damage while staying max range.
- Prioritize power chord Q on Vayne to reduce her trade potential, but save E power chord for disengage when Vel'Koz lands Q.
Wave Control/Roaming
- Don't roam in this matchup as your ADC needs constant protection from Vel'Koz poke and Vayne all-ins.
- Your sustain is crucial for maintaining lane presence against their superior scaling and zone control.
Mistakes to Avoid
- Never step forward to auto attack for power chord generation against Vel'Koz, as his Q-W combo will chunk you too hard.
- Don't use R defensively too early in teamfights, as Vel'Koz R will force you to use it suboptimally for positioning rather than engage.
Created on 01/09/2026
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