Who Wins
- You win pre-6 through levels 1-3 if you can gap close, as Vayne lacks escape tools and your full combo outdamages her early.
- Post-6 becomes significantly harder as her R gives invisibility and mobility to kite your engages while her damage scales up.
How to Trade
- Look for short trades using E-W-Q combo when she steps up for CS, then immediately disengage before she can proc three W stacks.
- Extended trades favor her due to W percent health damage and her ability to kite with Q repositioning.
Wave Control
- Push early waves to establish level advantage and zone her from CS, but be careful not to overextend past river.
- After level 6, maintain wave in center or slightly pushed to limit her all-in angles while keeping jungle proximity.
Mistakes to Avoid
- Don't chase her through minion waves where she can Q-tumble and use minions to block your skillshots.
- Avoid extended trades where she can proc multiple W stacks, as the percent health damage will quickly turn trades against you.
Created on 04/11/2026
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