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Pyke & Miss Fortune vs Ziggs & Milio
Bot Lane MatchupPyke vs Ziggs (with Miss Fortune & Milio) BOT matchup tips: who wins, how to trade, wave control and common mistakes.
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Who Wins
- Pre-6, you do not win the 2v2 cleanly — Ziggs' W slow and Q poke punish your hook attempts, and Milio's shield and heal keep the lane sustained against your burst.
- Post-6, you become a serious threat because your R resets give you kill potential, but only if you can land E through Ziggs' minion wave and Milio doesn't cleanse with his R.
Synergy & Trading
- Your best pattern is to use E from max range to hook Ziggs (not Milio) since Ziggs has no mobility to dodge and is the squishier target, then immediately Q stun and let Miss Fortune W-auto-Q for the kill.
- Avoid hooking Milio first — he has more utility to survive and his R will save Ziggs if you focus him.
Wave Control/Roaming
- You should roam aggressively once you hit level 6 and Miss Fortune has enough wave pressure to not lose tower — your R gold sharing makes roams extremely high value.
- Optimal roam timings are after a successful kill in lane or when the wave is pushed to their tower and Miss Fortune can safely hold, targeting mid where your E+R combo is lethal.
Mistakes to Avoid
- Do not use E blindly into the lane without vision of both enemies — Ziggs' W can slow you mid-dash and Milio can shield the target, turning your engage into a failed trade that leaves you overextended.
- Your passive healing requires you to stay in combat, so retreating after a failed hook puts you in a bad spot.
Created on 08/28/2026
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