Nasus vs Vayne
Top Lane MatchupNasus vs Vayne TOP matchup tips: who wins, how to trade, wave control and common mistakes.
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Who Wins
- You lose early trades heavily due to Vayne's range advantage and percent health damage, but post-6 you can threaten all-ins with W slow into R if she positions poorly.
- The matchup remains difficult throughout laning as her kiting tools make extended trades nearly impossible.
How to Trade
- Your only viable trading pattern is short Q trades when she steps up for CS, immediately backing off to avoid extended harass.
- Never commit to longer trades as her W proc and kiting with Q will chunk you heavily while you struggle to stick to her.
Wave Control
- You must freeze the wave near your tower to force Vayne into dangerous positions for CS and jungle gank setups.
- Pushing waves gives her free harass opportunities and makes you vulnerable to her E condemn into wall stuns.
Mistakes to Avoid
- Never chase Vayne through minion waves or into unwarded areas where she can E you into walls for easy stuns.
- Respect her E range and wall positioning at all times, as getting condemned into terrain often results in death or blown summoners.
Created on 06/07/2026
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