Mordekaiser vs Vayne
Top Lane MatchupMordekaiser vs Vayne TOP matchup tips: who wins, how to trade, wave control and common mistakes.
You
VS
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Who Wins
- You lose pre-6 to her range and kiting ability, struggling to land abilities consistently while taking free harass.
- Post-6 you become heavily favored as your R eliminates her positioning advantage and stolen stats make you nearly impossible to duel.
How to Trade
- Your trading pattern revolves around landing E pull to guarantee Q damage and stack passive, then using W shield to absorb her retaliation.
- Look for opportunities when she's farming or positioned poorly to engage with E-Q combo.
Wave Control
- Push waves aggressively to force her under tower where she struggles to farm safely and you can look for dives with jungle assistance.
- Use your waveclear advantage to roam for plays or recall without losing farm.
Mistakes to Avoid
- Don't chase her through minion waves early game where she can kite you indefinitely while you take minion damage.
- Avoid using abilities on cooldown without purpose as she will punish your windows of vulnerability with free harass.
Created on 04/12/2026
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