Miss Fortune & Senna vs Twitch & Brand
Bot Lane Matchup
You
VS
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Who Wins
- You lose level 2 due to Brand's instant burst potential and Twitch's stealth positioning advantage.
- You have a strong level 6 power spike with ultimate that can turn fights if positioned correctly behind minions.
Synergy & Trading
- Use Q bounces through low-health minions to poke while Senna provides sustain, then follow up with auto attacks when enemies are slowed by your E.
- Coordinate your ultimate with Senna's root for guaranteed damage.
Wave Control/Roaming
- Push for early level advantage to control the lane, then maintain minion waves between you and enemies to maximize Q bounce damage.
- Freeze near your tower post-6 to set up ultimate angles while staying safe from Twitch flanks.
Mistakes to Avoid
- Never use your ultimate without proper setup or vision as Brand can easily interrupt it with his stun.
- Don't walk up for CS without Senna's protection as Twitch can easily all-in you from stealth.
Created on 11/16/2025
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