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Who Wins
- Pre-6, you do not win a straight 1v1 if Annie has her stun ready — her burst with stun into W is enough to chunk you severely, and you have no reliable way to prevent the stun from landing if she plays patiently.
- Post-6, your R changes the matchup significantly: you can use it defensively to become untargetable during her combo, effectively wasting her stun window, or use it offensively after your E lands to lock her in place for your full rotation.
How to Trade
- Your best trading pattern is to use E to close the gap or reposition, then land W on her to slow and damage, followed by Q — never stand still in her auto-attack range, as her passive stun charges off autos too.
- Poke with Q at max range when safe, and only commit to a full trade when you have confirmed her stun is on cooldown.
Wave Control
- Use W to clear waves efficiently and maintain priority, which lets you roam or deny Annie's roam attempts; Lissandra's roam threat is a core part of how you win this lane, not by killing Annie directly.
- Avoid hard shoving into her tower repeatedly, as she can freely stack passive on the wave and you give her a safe environment to farm and wait for her stun.
Mistakes to Avoid
- Do not use your R offensively in this matchup unless you are certain Annie's stun is on cooldown — if she has the stun ready and you R onto her, she can simply Q you while you are locked in the animation and follow up with W, turning your all-in into a death.
Created on 08/13/2026
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